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Hi,

Bit of silly question. But when you give vitamin supplements in patients with cirrhosis, is it because of low intake in diet or that the liver cant metabolize the vitamins??



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carcinoma
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(Original post by A100whoo)
Hi,

Bit of silly question. But when you give vitamin supplements in patients with cirrhosis, is it because of low intake in diet or that the liver cant metabolize the vitamins??



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It depends which vitamins you are referring too.

Vitamin D deficiency occurs in cirrhosis as the second hydroxylation of vitamin d occurs in the liver. Therefore, they are at increased risk of osteoporosis.

Zinc deficiency is also common amount cirrhosis patients. The exact pathophys of that I don't know.

Also if they have alcoholic cirrhosis, b vitamins are replaced due to lack of dietary intake.

Are their any other vitamins you are specifically thinking about?


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member327593
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(Original post by carcinoma)
It depends which vitamins you are referring too.

Vitamin D deficiency occurs in cirrhosis as the second hydroxylation of vitamin d occurs in the liver. Therefore, they are at increased risk of osteoporosis.

Zinc deficiency is also common amount cirrhosis patients. The exact pathophys of that I don't know.

Also if they have alcoholic cirrhosis, b vitamins are replaced due to lack of dietary intake.

Are their any other vitamins you are specifically thinking about?


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Vitamin C? The pt was on vit b compound strong and ascorbic acid...
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Revenged
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are you sure you give vitamins to patients with cirrhosis ? i thought it is for alcoholics and you give it irrespective of liver damage. lack of thiamine causes wernicke's encephalopathy and later korsikoff's which are very serious . you give vitamin B co-strong and thiamine tablets to alcoholics because of lack of it in the diet and it prevents these neurological conditions. vitamin C we normally give it in IV pabrinex in withdrawal prevention but sometimes you give it as a tablet.

the only vitamin i give a lot in patients with cirrhosis is vitamin K. this is made in the liver and you need it for clotting. cirrhotic patients dont produce it so you need to replace it before you do procedures like paracentesis as typically there clotting/INR goes off. zinc/vitamin D deficiency, not really heard of it being measured or replaced. HTH
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