I looked at the clearing page last results day and I don't think Manchester was on there unfortunately, it is very competitive for Pharmacy. Was your medical reason in your reference?
It's great that you've already got a Durham offer, they have the same number of places as last year I think and apparently last year they didn't give out that many offers at all. Durham is a beautiful university, very very highly ranked in league tables, I'm sure you'd do brilliantly there. It depends on what you like though really, personally I absolutely hated Manchester, horrible city, no proper 'campus' as such, accommodation was vile and the pharmacy talk was so uninspiring, oh and apparently it's a lot more problem based learning than other uni's (less proper teaching). I wanted to go there originally but after the open day I decided not to apply at all. Each to their own though