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How does the phospholipid bilayer prevent water soluble substances entering the cell?

How does the phospholipid bilayer prevent water soluble substances entering the cell?

Any help will be greatly appreciated.

Reply 1

Nirgilis

Moved to biology help for you :h:

Reply 2

onefour

It's to do with the chemical properties of the bilayer - the interior of the bilayer is comprised of hydrophobic lipid chains which physically exclude water-soluble substances because they are hydrophilic.

Reply 3

x__justmyluck

Polar molecules cannot move through the non-polar region of the membrane.

Reply 4

Alltimesarah

Could cholesterol come into this as it controls fluidity?

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