hmmm.. difficult situation. sometimes the hardest thing is to try and help people who don't want to be helped. In the end, all you can do is be there for her - reassure her that you'll always be around and that what matters to you is the person she is, not what size she is. Have you ever thought that maybe by making an issue of her eating (e.g. making sure she eats when you go out etc) is just making it more of a problem? Maybe, and I don't mean to be harsh, only put across another view, in some way she likes the attention that she gets from not eating, and that by commenting on it, that you're fuelling her whole obsession? Of course, I don't know your friend, or you at all, but I do know people who think like this. Perhaps the best thing to do is not to comment on what she is doing - talk of other things. She'll only stop when she wants to, and the harsh truth is that no-one else can make her, no matter how bad it gets.