Why do blisters form when you get chickenpox?Watch this thread
I know one of the symptoms of chicken pox are blisters, but why do they form?
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"In chickenpox the virus, which has been hanging out in your neurons, begins to travel down the nerves to get to the skin. Once there it sets up shop in skin cells and begins to replicate.
(the rest of this is pieced together from a variety of public science databases, so grain of salt):
To get the the skin, the virus actually hitches a ride on T-cells, one of your body's most important immune cells.
The virus is able escape the attention of the immune system for a while in the skin and reproduces rapidly.
(mostly speculative info on my part here):
Because the virus infects the lower layers of the skin first, the damage and inflammation causes by the virus' replication causes a void under the skin which is filled by inflammation and clear liquid (probably similar to lymph). The same sort of phenomena can be observed when you get a Tuberculosis skin test. The healthcare worker injects a small amount of fluid into the upper layer of your skin causing the formation of a small, raised bump. However, with the TB test, because there is no ongoing inflammation the fluid is quickly re-absorbed, unlike in chickenpox where there is continual activation of inflammation and likely an influx of immune system cells.
So, the TL;DR is that Chickenpox causes vesicles (blisters) by creating a strong, localized inflammation and cell death in the lower layers of the skin causing a raised, fluid-filled bubble."