DNA formula.

Hello, people!

I was reading a little bit about DNA and i was wondering, if DNA is an acid, what is his formula?
Could someone tell me? Is there a H in front of the rest of the formula?

Thank you!

Reply 1

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Original post by amanda.castro

Hello, people!

I was reading a little bit about DNA and i was wondering, if DNA is an acid, what is his formula?
Could someone tell me? Is there a H in front of the rest of the formula?

Thank you!

DNA is an acid (Deoxyribonucleic acid) and is made of of loads and loads of copies of the same constituent base pairs (Adenine, Guanine, Cytosine and Thymine) which are bonded in a certain shape. It also has a sugar phosphate backbone and 2-deoxyribose.

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Reply 2

Kallisto

Entertainment Forum Helper

As you surely know the DNA consists of three bonds: phosphate, deoxyribose and the four bases (adenine, guanine,cytosine and thymine). I have never seen that a formula for DNA exists, but if we consider that the phosphate bonds are outside of a DNA strand, followed by the deoxyribose ones and the bases in the middle, so you can form this pattern:

phosphate - deoxyribose - base 1 - base 2 - deoxyribose - phosphate.

The phosphates and the deoxyribose bonds are fixed, while the bases are free. By this pattern, there are four possibilities for bases:

adenine (base 1) - thymine (base 2)
thymine - adenine
guanine - cytosine
cytosine - guanine

Reply 3

laura.g.berger

...but if we consider that the phosphate bonds are outside of a DNA strand, followed by the deoxyribose ones and the bases in the middle, so you can form this pattern: ...

So, if were possible to make chemical reactions with DNA, the first affected would be the outermost oxygens of the phosphate and then the deoxyribose and so on until the innermost part of the DNA?

Reply 4

Kallisto

Entertainment Forum Helper

Original post by laura.g.berger

So, if were possible to make chemical reactions with DNA, the first affected would be the outermost oxygens of the phosphate and then the deoxyribose and so on until the innermost part of the DNA?

I have never heard about chemical reactions by which a DNA strand is involved. It is possible to link an DNA segment with another one by sticky ends, but reactions with something? No, not to my knowledge.

Reply 5

laura.g.berger

Original post by Kallisto

It is possible to link an DNA segment with another one by sticky ends...

How this is done?

Reply 6

Kallisto

Entertainment Forum Helper

Original post by laura.g.berger

How this is done?

I don't know the method, but the principle works as follows: two DNA strands are split in four segments. After that two segments of them are recombinated to a new DNA strand. The one strand is the backbone, while the other one is the insert. If these strands come together, so it causes a ligation and the recombination of the new strand is perfect.

Here is a picture of it: http://www.addgene.org/static/cms/images/ligation.gif

Reply 7

Borek

Original post by Kallisto

I have never heard about chemical reactions by which a DNA strand is involved.

I guess it depends on how you define the "reaction of DNA". To some extent methylation could count - the -CH₃ is added to the nucleotides being part of the DNA strand.

Reply 8

Kallisto

Entertainment Forum Helper

Original post by Borek

I guess it depends on how you define the "reaction of DNA". To some extent methylation could count - the -CH₃ is added to the nucleotides being part of the DNA strand.

Oh, now you mention it, I can remember. Yes that can be counted as reaction. Thanks that you have refreshed my mind!

Reply 9

laura.g.berger

Original post by Kallisto

Do you know where i can read more about this? Maybe an article. I read that you can replace the "P" of the phosphate by an "C" or others elements, but most common is "C", i don't know if this count like chemical reaction too.