Enzymes and PH question ??Watch this thread
Explain in detail why and how enzymes can be affected by changes in PH ?
Just for a brief overview, pH can disturb the bonds in the protein structure of the enzyme. This can in turn lead to protein denaturation and loss of enzyme activity, since enzymes need a specific configuration for their action as catalysts. A low pH would disrupt the basic bonds, while the reverse would be true for a high pH. Conversely, pH can affect the substrate as well.
This will help for a brief intro.