I ended up with AAAbc in English Lit, English Lang, History, Critical Thinking and Biology.
When I started the sixth form I wanted to continue with all four (eng, eng, hist and bio) to A2, but hated Biology with such a passion that continuing with it wasn't really an option. Do what you're comfortable with. Continuing with a subject that you find hard might end up dragging down your other grades, as you'll have to concentrate on your weakest subject.