The buff Yahooey suggests focussing heavily on a full body compound routine and not a split routine. The buff Yahooey thinks that because protein synthesis returns to baseline levels between 48-72 hours after working a muscle, that working a muscle 2-3 times a week is optimum.
The buff Yahooey also thinks that there is little point in isolating muscle at your size, since using muscles such as traps, triceps and biceps as ancilliary muscles to aid in bigger compound lifts such as bench presses, deadlifts, pullups, rows, military presses etc. will bulk them up along with the primary muscles you are using for the lifts.
The buff Yahooey suggests that if you are looking for a 4 day workout plan, that it should look something like this:
Monday:
Barbell bench press x 5 sets
Squats x 6 sets
Military press x 5 sets
Tuesday:
Deadlift x 6 sets
Weighted wide grip pullups x 5 sets
Bent over dumbbell rows x 5 sets
Wednesday:
Rest
Thursday:
Dumbbell bench press x 5 sets
Squats x 6 sets
Dumbbell shoulder press x 5 sets
Friday:
Deadlift x 6 sets
Ultra wide grip pullups x 5 sets
Bent over barbell rows x 5 sets
The buff Yahooey thinks that this routine gives you plenty of rest, and that 16 sets per workout is not too much, but it's also little enough that you have room to work your abs if you want, and also if you feel that your traps, biceps, triceps, lower back or whatever need some isolation work because they're not getting fatigued enough with the compound lifts that you can throw a few isolations in there as well.
The buff Yahooey has spoken.