I was responding to people who were stating whether x amount of A*'s was appropriate, or people were saying that less than 5A*'s and you're pretty much rejected. Sorry, should've been more clear
In regards to lower GCSEs:
In my opinion with <6-8 A's at GCSE, your chances are low, purely due to the amount of universities that you can apply to. For example, with 5A's you may only have 10 universities that will definitely consider you, then if you happen to do poorly on your UKCAT then that number lowers, so you're limited - it's definitely not impossible.
In regards to the OP, your GCSEs are strong, there is no doubt about that. Unfortunately, due to the amount of applicants to medicine, it is unlikely, even with 4As at AS that you will receive an interview. It is possible though, you will be very limited with your university choices - I strongly recommend that you ring up individual universities and ask. Also, prepare for your UKCAT, as you'll need something to really balance out your lower GCSEs. Try do it a month before the October deadline, so you have time to ring up universities and decide. You will really have to apply strategically. Assuming 4 A's AS and a high UKCAT it is definitely possible for you to get an interview.
Otherwise there are many courses that offer access to medicine. This means that you do a one year course then at the end of that depending on performance and non-academic things you may get an interview and subsequent offer for medicine at their linked university.
What you really have to decide is whether you want to
- apply to medicine once or try two times (with a gap year);
- have a backup of an access course, or have a backup of a scientific-degree with career prospects that you would enjoy with the option for grad med;
- have a backup of an non-scientific degree which you would enjoy, but without the possibility of grad med;
- apply to 5 non-medicine degree choices and either try for access/graduate later on.
- apply abroad
I would not recommend doing a gap year if you do not get in first time due to your GCSEs, as no amount of extra work experience / volunteering will change academic achievements.
Personally, if you are really committed to medicine, then I would apply to UCAS for medicine (as you have to do so anyway), then have a backup of an access course - which you should have no problem getting into.
When you want to transfer from an access course to the med school then they generally do not look at previous academic achievement - just the one year in university. So that should give you a good shot. You can also complete she access course (3-4 years) and try for grad med.