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Secondary Active Transport.

I need to consider what will happen to secondary active transport, that relies upon the energy that can be harnessed through the established Na+ ionic gradient across the cell membrane at rest, after depolarisation.

Must be a mind block- but the only reason I can think of is that as the ionic gradient still exists, just in the opposite direction, the movement of ions such as calcium via antiport cotransporters will just occur in the opposite direction to when the resting potential was established across the membrane.

Any other more significant idea's you can think of?

Thanks in advance
Yours,
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