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Butterfliesandlions20
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What is the therpeautic advantage of reversibility of action on enzyme inhibitors?

Can anybody explain? Thanks
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Shadoo
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(Original post by ninahstah)
What is the therpeautic advantage of reversibility of action on enzyme inhibitors?

Can anybody explain? Thanks
The therapeutic advantage of reversibility of the action of enzyme inhibitors means that the effect of the inhibitor on the enzyme can be reversed at a certain time. One example of this is in Chemo therapy the drug methotrexate which inhibits an enzyme involved in Nucleotide production it would stop the rapidly growing cancer cells from replicating but healthy cells would not be affected as the effect of the inhibitor would have wore off by the time they replicate.
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Butterfliesandlions20
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(Original post by Shadoo)
The therapeutic advantage of reversibility of the action of enzyme inhibitors means that the effect of the inhibitor on the enzyme can be reversed at a certain time. One example of this is in Chemo therapy the drug methotrexate which inhibits an enzyme involved in Nucleotide production it would stop the rapidly growing cancer cells from replicating but healthy cells would not be affected as the effect of the inhibitor would have wore off by the time they replicate.
So is the question asking why are reversible inhbitiors advantageous? Also, do you know the therapeutic advantage of acetylcholinesterase?

Thank you!
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Shadoo
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(Original post by ninahstah)
So is the question asking why are reversible inhbitiors advantageous? Also, do you know the therapeutic advantage of acetylcholinesterase?

Thank you!
It is asking why they are useful for therapeutic reasons which means why are they useful in medicine. I assume your talking about the inhibitors of acetylcholinesterase and they are useful because they can be used to treat Alzheimers patients. I'm being brief here so you may want to research the topics in more depth. I'm pretty sure you can find something about acetylcholinesterase inhibitors on google and their use for the treatment of alzheimers.
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Butterfliesandlions20
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(Original post by Shadoo)
It is asking why they are useful for therapeutic reasons which means why are they useful in medicine. I assume your talking about the inhibitors of acetylcholinesterase and they are useful because they can be used to treat Alzheimers patients. I'm being brief here so you may want to research the topics in more depth. I'm pretty sure you can find something about acetylcholinesterase inhibitors on google and their use for the treatment of alzheimers.
Yes I have researched AD and also myasthenia gravis, I just could not get my head around the question. Now you have made it clearer for me, it is asking for their advantages in medicine, so that is why I would relate it to AD and myasthenia gravis. Thank you!
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(Original post by ninahstah)
Yes I have researched AD and also myasthenia gravis, I just could not get my head around the question. Now you have made it clearer for me, it is asking for their advantages in medicine, so that is why I would relate it to AD and myasthenia gravis. Thank you!
No problem D: If i helped you, you can hit the rep button :P
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