1drowssap
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Hi,

Just learnt about Karposi's Sarcoma recently. I'm really confused as to whether it arose from the abnormal growth in the epithelial cells or connective tissue.
I know Sarcoma means malignant neoplasm of connective tissue, but some sites seem to suggest that it is due to abnormally growing blood vessels(which could be due to abnormal growth of epithelial(endothelium/tunica intima) or connective tissue(tunica media, tunica externa).

For some reason, I'm not entirely convinced it is a "sarcoma". The wording 'lining of the blood vessels' (which implicitly means endothelium) in the link below really makes it more confusing.
http://www.cancer.org/cancer/kaposis...kaposi-sarcoma

Could someone help me clarify this?
Thank you so much.
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Asklepios
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(Original post by 1drowssap)
Hi,

Just learnt about Karposi's Sarcoma recently. I'm really confused as to whether it arose from the abnormal growth in the epithelial cells or connective tissue.
I know Sarcoma means malignant neoplasm of connective tissue, but some sites seem to suggest that it is due to abnormally growing blood vessels(which could be due to abnormal growth of epithelial(endothelium/tunica intima) or connective tissue(tunica media, tunica externa).

For some reason, I'm not entirely convinced it is a "sarcoma". The wording 'lining of the blood vessels' (which implicitly means endothelium) in the link below really makes it more confusing.
http://www.cancer.org/cancer/kaposis...kaposi-sarcoma

Could someone help me clarify this?
Thank you so much.
Sarcoma doesn't just mean connective tissues. It means malignant neoplasm of cells with a mesenchymal origin. This is mainly connective tissue yes, but also lyphatics, blood vessels and muscle.

Kaposi sarcoma is is of the endothelium. Carcinomas are only of epithelia.
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1drowssap
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(Original post by Asklepios)
Sarcoma doesn't just mean connective tissues. It means malignant neoplasm of cells with a mesenchymal origin. This is mainly connective tissue yes, but also lyphatics, blood vessels and muscle.

Kaposi sarcoma is is of the endothelium. Carcinomas are only of epithelia.
Thanks. That makes so much more sense. My lecturer made it so much more confusing by labeling malignant neoplasms of connective tissue as sarcoma(which I now know is not always the case), and labeling malignant neoplasms of epithelial tissue as carcinoma.
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