Back
to top
Hyponatraemia Help!
Watch
Announcements
Page 1 of 1
Go to first unread
Skip to page:
Does anybody have a simple way of explaining the different types of hyponatraemia?! So we are supposed to be looking at it in more of a clinical context but need to know the pathophysiology of the various types - hypovolaemic, euvolaemic, and hypervolaemic.
Euvolaemic hyponatraemia is seriously confusing me as all of the textbooks that I've read say that this is effectively a dilution hyponatraemia but that the body sodium level has not altered. I know that SIADH is a cause, but in this context, I assumed that the hyponatremia was (as I've read) dilutional due to the inappropriate reabsorption of water. If this is the case, how is it not hypervolaemic?
Clear as mud what I'm asking? I hope people can understand...much appreciated x
Euvolaemic hyponatraemia is seriously confusing me as all of the textbooks that I've read say that this is effectively a dilution hyponatraemia but that the body sodium level has not altered. I know that SIADH is a cause, but in this context, I assumed that the hyponatremia was (as I've read) dilutional due to the inappropriate reabsorption of water. If this is the case, how is it not hypervolaemic?
Clear as mud what I'm asking? I hope people can understand...much appreciated x
0
reply
Report
#2
(Original post by Dr.Diplodocus)
Does anybody have a simple way of explaining the different types of hyponatraemia?! So we are supposed to be looking at it in more of a clinical context but need to know the pathophysiology of the various types - hypovolaemic, euvolaemic, and hypervolaemic.
Euvolaemic hyponatraemia is seriously confusing me as all of the textbooks that I've read say that this is effectively a dilution hyponatraemia but that the body sodium level has not altered. I know that SIADH is a cause, but in this context, I assumed that the hyponatremia was (as I've read) dilutional due to the inappropriate reabsorption of water. If this is the case, how is it not hypervolaemic?
Clear as mud what I'm asking? I hope people can understand...much appreciated x
Does anybody have a simple way of explaining the different types of hyponatraemia?! So we are supposed to be looking at it in more of a clinical context but need to know the pathophysiology of the various types - hypovolaemic, euvolaemic, and hypervolaemic.
Euvolaemic hyponatraemia is seriously confusing me as all of the textbooks that I've read say that this is effectively a dilution hyponatraemia but that the body sodium level has not altered. I know that SIADH is a cause, but in this context, I assumed that the hyponatremia was (as I've read) dilutional due to the inappropriate reabsorption of water. If this is the case, how is it not hypervolaemic?
Clear as mud what I'm asking? I hope people can understand...much appreciated x
it is low sodium in blood not low water,
http://www.mayoclinic.org/diseases-c...n/con-20031445
0
reply
Yes but hyponatraemia is subdivided into hypovolaemic, euvolaemic and hypervolaemic...?
0
reply
Report
#4
(Original post by Dr.Diplodocus)
Does anybody have a simple way of explaining the different types of hyponatraemia?! So we are supposed to be looking at it in more of a clinical context but need to know the pathophysiology of the various types - hypovolaemic, euvolaemic, and hypervolaemic.
Euvolaemic hyponatraemia is seriously confusing me as all of the textbooks that I've read say that this is effectively a dilution hyponatraemia but that the body sodium level has not altered. I know that SIADH is a cause, but in this context, I assumed that the hyponatremia was (as I've read) dilutional due to the inappropriate reabsorption of water. If this is the case, how is it not hypervolaemic?
Clear as mud what I'm asking? I hope people can understand...much appreciated x
Does anybody have a simple way of explaining the different types of hyponatraemia?! So we are supposed to be looking at it in more of a clinical context but need to know the pathophysiology of the various types - hypovolaemic, euvolaemic, and hypervolaemic.
Euvolaemic hyponatraemia is seriously confusing me as all of the textbooks that I've read say that this is effectively a dilution hyponatraemia but that the body sodium level has not altered. I know that SIADH is a cause, but in this context, I assumed that the hyponatremia was (as I've read) dilutional due to the inappropriate reabsorption of water. If this is the case, how is it not hypervolaemic?
Clear as mud what I'm asking? I hope people can understand...much appreciated x
My two pennies...
Basic facts:
- Aldosterone acts to reabsorb water and sodium in a relatively physiological ratio
- ADH however acts to reabsorb water well in excess of sodium
- ADH can boost your volume state in an emergency eg., blood loss which is why haven't evolved out of it
In SIADH (or other non-osmotic ADH state):
- You would expect to get hypervolemic hyponatremia as explained above
- However your levels of aldosterone will drop to counter the hypervolemia
- Lowering the aldosterone won't change the ratio of salt to water, but will decrease levels of both in roughly equal measures
Hope that helps!
1
reply
(Original post by Tech)
I think I understand your question.
My two pennies...
Basic facts:
- Aldosterone acts to reabsorb water and sodium in a relatively physiological ratio
- ADH however acts to reabsorb water well in excess of sodium
- ADH can boost your volume state in an emergency eg., blood loss which is why haven't evolved out of it
In SIADH (or other non-osmotic ADH state):
- You would expect to get hypervolemic hyponatremia as explained above
- However your levels of aldosterone will drop to counter the hypervolemia
- Lowering the aldosterone won't change the ratio of salt to water, but will decrease levels of both in roughly equal measures
Hope that helps!
I think I understand your question.
My two pennies...
Basic facts:
- Aldosterone acts to reabsorb water and sodium in a relatively physiological ratio
- ADH however acts to reabsorb water well in excess of sodium
- ADH can boost your volume state in an emergency eg., blood loss which is why haven't evolved out of it
In SIADH (or other non-osmotic ADH state):
- You would expect to get hypervolemic hyponatremia as explained above
- However your levels of aldosterone will drop to counter the hypervolemia
- Lowering the aldosterone won't change the ratio of salt to water, but will decrease levels of both in roughly equal measures
Hope that helps!
Thank you!
0
reply
X
Page 1 of 1
Go to first unread
Skip to page:
Quick Reply
