Shani148
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Hi, I've just completely confused myself with the immunity topic for AS biology. The question I'm trying to answer is "Describe how antibodies are produced in the body following a viral infection."

I thought that when the body is invaded by foreign material it must be cell mediated immunity, which is T-cells, that don't produce antibodies, so I don't understand how they come into this question?

And I'm confused as to whether B-cells are solely Humoral Immunity and they only recognise self material? Does T-cell and cell mediated immunity occur first in specific responses, build up T cells, and then humoral immunity causes B-cells to divide?

Any help would be appreciated! THANK YOU!
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s_________
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T cells is cell mediated
They have T helper cells which bind to the antigens and activate them for response by triggering antibody production and they don't ever provide antibodies
B cells are humoral and provide the antibodies for the antigens
It's usually T cells before B cells
If you get the Steve Potter AS textbook for AQA it's much better and more helpful than using the Toole Nelson Thornes textbook
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Shani148
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(Original post by selenerrr__x)
T cells is cell mediated
They have T helper cells which bind to the antigens and activate them for response by triggering antibody production and they don't ever provide antibodies
B cells are humoral and provide the antibodies for the antigens
It's usually T cells before B cells
If you get the Steve Potter AS textbook for AQA it's much better and more helpful than using the Toole Nelson Thornes textbook
Thank you! I will probably end up getting that one then, because I'm currently using the nelson thornes one and its so confusing! So, T-cells don't produce AB and are usually prior to B cells, so how are AB produced for viruses when viruses are foreign and cell mediated?
THANKYOU!
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s_________
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The Nelson thornes is terrible and they do miss out a lot of information (definitely for unit 2 get it)
I think it's the same for both foreign and non foreign
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Dynamo123
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(Original post by Shani148)
Thank you! I will probably end up getting that one then, because I'm currently using the nelson thornes one and its so confusing! So, T-cells don't produce AB and are usually prior to B cells, so how are AB produced for viruses when viruses are foreign and cell mediated?
THANKYOU!
T cells do not form antibodies, they form activated T cells. However, the helper T cells release certain chemical substances on exposure to any foreign antigen (from virus f.i.). These are called lymphokines. Lymphokines such as interleukins 4,5,6 stimulate B cells to multiply. B cells then form plasma cells, which start forming related antibodies.

B cells can also be directly stimulated to produce antibodies by exposure to foreign antigen. However, this is relatively weak.
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s_________
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This animation helped me a bit about T and T helper cells
http://highered.mheducation.com/olc/...10/micro33.swf
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Shani148
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(Original post by selenerrr__x)
This animation helped me a bit about T and T helper cells
http://highered.mheducation.com/olc/...10/micro33.swf
THANKYOU! Much appreciated!!:cool:
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s_________
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I should've linked this as well, generally
All my old schs have used these resources in class
http://highered.mheducation.com/olc/...animation.html
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