I believe that all Access Courses now require at least grade C in GCSE Maths and English from September 2014... You would certainly need them (or an equivalent) to get onto a uni nursing course.
Access courses fit in well when you have other commitments and do prepare you for uni.
It seems like a long time doing GCSEs for a year, then access for a year but it really does go so quickly.
I believe there is an option to do nursing training with the nhs when you already work for them. I think it takes four years and its hard to get accepted. I don't know a lot about it im afraid.