I've literally just got back from an Msc Medicinal Chem inteview at Leeds. It was nerve wrecking, and I love interviews! But, I'm a mature student so they gave me a proper grilling. As far as student satisfaction goes, the first few years of Medicinal Chemistry is straight Chemistry until year 3 where you choose more specific units for your degree. Bear in mind though that straight chemistry often has up to 150 students, maybe that contributes to the lower grade?