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    In Tissue engineering, hepatoctypes are isolated and cultured, scaffolded and inserted in to the body.

    Numerous citations state this can only be done in vitro, why can hepatocytes not be grown in vivo?

    thanks in advance :-)
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    The scaffolding involves putting the new cells in already existing extracellular matrix without its old cells, which have been removed by decellularisation. It presumably can't be done in vivo because there is no empty extracellular matrix for them to be placed/grow in.
 
 
 
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