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Dexamphetamine

14

Alright so I take dexamphetamine to help me with my ADHD. It's essentially saved my education existence. One of the major pros of this drug is stamina. I have super stamina.

I was wondering if anyone here knows anything about the drug?
If I have this feeling of increased stamina, and I run much more than I usually could, will I damage my body or will I help create a natural increase in stamina so that when I'm not on the drug I can run more?

Reply 1

Eblis_O'_Shaughnessy

5

Assuming you don't push yourself so hard something bad happens, it's only going to do good things for your fitness.

Reply 2

Fluffy

15

Make an appointment to speak to your doctor - they should be the one answering your questions...

In the interim, and to inform any discussion you might want to have:
http://www.gpnotebook.co.uk/simplepage.cfm?ID=1845887055
http://www.bnf.org/bnf/bnf/52/3374.htm?q=%22dexamphetamine%22
http://hcd2.bupa.co.uk/fact_sheets/html/attention_deficit.html

Reply 3

Deus

OP

14

Thank you for the links Fluffy.

Reply 4

Revenged

15

Deus

Alright so I take dexamphetamine to help me with my ADHD. It's essentially saved my education existence. One of the major pros of this drug is stamina. I have super stamina.

Amphetamine is "speed"... It is a recreational drug that is a very strong stimulant... It's mechanism of action causes increased nerve innervation to muscles... So no wonder it increases your stamina...

Why it is given for people with ADHD is beyond me... Doesn't it cause drug addition?

Reply 5

Deus

OP

14

I take it in a small dose. It's a small pill that has a 4-6 hour effect. It simply removes this urge to run around and be distracted by everything.

Reply 6

Alewhey

Revenged

Amphetamine is "speed"... It is a recreational drug that is a very strong stimulant... It's mechanism of action causes increased nerve innervation to muscles... So no wonder it increases your stamina...

Dextroamphetamine ≠ Methamphetamine

Revenged

Why it is given for people with ADHD is beyond me

Could that be because you don't know what you are talking about?

Reply 7

Revenged

15

Deus

I take it in a small dose. It's a small pill that has a 4-6 hour effect. It simply removes this urge to run around and be distracted by everything.

Yeah... I'll take your word for it... but that doesn't make much sense to me... Amphetamine is a stimulant and should make you want to run about like crazy... That's why people use it's a recreational drug...

Reply 8

Eblis_O'_Shaughnessy

5

Revenged

Yeah... I'll take your word for it... but that doesn't make much sense to me... Amphetamine is a stimulant and should make you want to run about like crazy... That's why people use it's a recreational drug...

Booze is a depressant though, and look what happens when people go out and get pissed.

It's a crazy world.

Reply 9

Revenged

15

Alewhey

Dextroamphetamine ≠ Methamphetamine

Could that be because you don't know what you are talking about?

But both of them are amphetamines... :rolleyes:

And who are you to said to me that I don't know what I'm talking about... I probably know a hell of a lot more than you do...

Reply 10

Revenged

15

Eblis_O'_Shaughnessy

Booze is a depressant though, and look what happens when people go out and get pissed.

It's a crazy world.

Yep, it certainly is a crazy world... :wink:

Reply 11

Fluffy

15

It's all about dopamine. At their therapeutic doses, both dexamphetamine and methylphenidate are thought to lead to an increased release of dopamine in the brian (through different mechanisims... IIRC, dexamphetamine increases dopamine synthesis and blocks its reuptake, while methylphenidate releases preformed dopamine).

Reply 12

danesh

Fluffy

It's all about dopamine. At their therapeutic doses, both dexamphetamine and methylphenidate are thought to lead to an increased release of dopamine in the brian (through different mechanisims... IIRC, dexamphetamine increases dopamine synthesis and blocks its reuptake, while methylphenidate releases preformed dopamine).

yup, dead on:

dexamfetamine has three (i believe) actions, blocking the NA/DA reuptake transporter, partially inhibiting MAO A/B, and displacing NA/DA directly from the neurone - as such it's an indirect simpathomimetic.

Methylphenidate is similar, though it does not inhibit MAO A/B to the same extent and has more selectivity for DA neurons.

Reply 13

Revenged

15

Fluffy

It's all about dopamine. At their therapeutic doses, both dexamphetamine and methylphenidate are thought to lead to an increased release of dopamine in the brian (through different mechanisims... IIRC, dexamphetamine increases dopamine synthesis and blocks its reuptake, while methylphenidate releases preformed dopamine).

Ok, cheers... I didn't realise that it was a centrally acting... The only amphetamine I've come across is tyramine, which acts mainly on peripheral nerves...

Reply 14

Deus

OP

14

So I'm surrounded by geniuses. Well glad I know a little bit more about the drug that I take. So far I don't suffer from any negative effects, but obviously I don't take much and I don't take it often (generally just before exams, or tests).

Thanks again for all the information.

Reply 15

Fluffy

15

Revenged

Ok, cheers... I didn't realise that it was a centrally acting... The only amphetamine I've come across is tyramine, which acts mainly on peripheral nerves...

Tyramine is a monoamine, not an amphetamine (although both are indirectly-acting sympathomimetic amines - as they are structurally related to noradrenaline) - it is derived from the breakdown fo the amino acide tyrosine.

Tyramine doesn't usually enter the CNS, as it is broken down by mono-amine oxidases. That said look up "the cheese effect"/"cheese reaction" to see what happens when MAO is inhibited (as is the case in one class of antidepressants, the MAOIs") in the presence of dietary tyrosine/tyramine...

Reply 16

InArduisFouette

21

Eblis_O'_Shaughnessy

Booze is a depressant though, and look what happens when people go out and get pissed.

It's a crazy world.

alcohol is a depressent - it depresses the parts of your brain that control behaviour first - if you drink through that to the point of collapse you have managed to depress all sorts of functions - hence the phenomena of being 'dead drunk' when very painful stimuli end up being used by EMS and hospital personnel to check you ...

the fact that ampehetamine group drugs are used in ADHD treatment / symptom control is not odd given that medicine also prescribes the majority of drugs of abuse for legitmiate purposes ( opiates, benzos, ketamine, ntirous ...)