capnUSA
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Report Thread starter 4 years ago
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Hello, I've got a sheet with a gazillion questions and these are like the 4 main questions I don't understand,

why don't normal cells form tumours?
Why does the cell become cancerous?
What is a tumour?
What is metasis?

Can someone help me please? I'd appreciate it a lot,
thank you
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Joshalos
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(Original post by capnUSA)
Hello, I've got a sheet with a gazillion questions and these are like the 4 main questions I don't understand,

why don't normal cells form tumours?
Why does the cell become cancerous?
What is a tumour?
What is metasis?

Can someone help me please? I'd appreciate it a lot,
thank you
1. Normal cells don't form tumours because their growth and division is tightly controlled in the cell cycle. They only reproduce when they are needed and at certain points in the cell cycle, they reach check points to ensure the cell is dividing as it should - for example, one check point ensures that the chromosomes are correctly aligned so that the correct number of chromosomes are in each cell.

2. These checkpoints don't occur in cancerous cells since mutations in the DNA affect proteins which control these checkpoints and allow the cell to divide uncontrollably.

3. A tumour is an uncontrolled mass of dividing cells. A tumour can be benign meaning that it is confined to one part of the body and remains as part of the tissue it originated from. A tumour is considered cancer until it becomes malignant, i.e. it begins to invade the surrounding tissues or metastasises.

4. Metastasis is when parts of the tumour break off and enter the circulation or lymphatic system and spreads around the body. It then comes to rest at a secondary site where oncogenesis (literally 'creation of cancer') can continue and a secondary tumour can form. Common sites for metastases to occur are the bone, liver and lung as well as the lymph nodes.
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capnUSA
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Report Thread starter 4 years ago
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thank you so so much!!
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