Esteta
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#1
Report Thread starter 6 years ago
#1
Hey guys,
I'm currently doing a research project on aspirin and wanted to take pharmaceutical grade aspirin and see how different conditions affect the purity....Has anyone ever done anything like this before?

Otherwise im screwed!
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Esteta
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#2
Report Thread starter 6 years ago
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Ha ok, do you think leaving aspirin in different conditions will affect the solubility of it? Please help. For example leaving it in a place which is really damp, exposed to sunlight etc.
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claireestelle
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#3
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I presume no ones every tried that, doesnt sound particularly safe...
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Esteta
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#4
Report Thread starter 6 years ago
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(Original post by claireestelle)
I presume no ones every tried that, doesnt sound particularly safe...
Which part doesn't sound safe?
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thegodofgod
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#5
Report 6 years ago
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(Original post by Esteta)
Ha ok, do you think leaving aspirin in different conditions will affect the solubility of it? Please help. For example leaving it in a place which is really damp, exposed to sunlight etc.
Hmm, aspirin is acetylsalicylic acid (ASA), so keeping it in humid conditions will cause it to degrade by hydrolysis and lose its pharmacological activity.

Hydrolysing ASA will form acetic acid and salicylic acid. I presume having more OH bonds would cause it to be more soluble in an aqueous solution?
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Esteta
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#6
Report Thread starter 6 years ago
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I'm just so stuck. I've done all of my research on aspirin and can't think of something which I can test on pharmaceutical grade aspirin. I keep thinking about different conditions on the solubility. Does anyone have any ideas?
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