The importance of Diagnostic EnzymesWatch this thread
Some enzymes are used commercially, for example, in the synthesis of antibiotics. Some household products use enzymes to speed up chemical reactions. Enzymes in biological washing powders break down protein, starch or fat stains on clothes, and enzymes in meat tenderizer break down proteins into smaller molecules, making the meat easier to chew.
And another importance of enzymes in medicine at present at the measurement of enzymes levels as an acid to diagnosis. They are used to determine the level of the specific enzymes present in the blood, urine, body fluids or tissues.
Enzymes are the preferred markers in various diseases; they also provide insight into the disease process by diagnosis, prognosis and assessment of response therapy. Enzymes are preferred in diagnostics because their substrate specificity and their activity can be measured in the presence of other proteins.
Diagnostic enzymes are also important in estimating the concentration of a substances and metabolites. Progress has been obtained in diagnosis because a wider variety of pure and stable enzymes. Many of the enzymes tests are easy to assay and automate. These tests are offend proffered over older test because the differences between the normal specimen and the disease specimen are clearly demonstrate and diagnostically significant. The enzyme utilize are sufficiently stable and allow storage for a limited but reasonable time. With these advances there has been a parallel increase in laboratory research utilizing similar sophisticated techniques and equipments.
Since the tight control of enzyme activity is essential for homeostasis, any malfunction (mutation, overproduction, underproduction or deletion) of a single critical enzyme can lead to a genetic disease. The malfunction of just one type of enzyme out of the thousands of types present in the human body can be fatal. An example of a fatal genetic disease due to enzyme insufficiency is Tay-Sachs disease, in which patients lack the enzyme hexosaminidase.
They are present in the plasma as a result of other body problems, such as liver disease, heart attacks, and muscle diseases, diseases of the pancreas or cancer. Examples include some phosphatases, transaminases, lipases and amylases.
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