The Student Room Group
Reply 1
The liver is one of the largest internal organs of the body. It therefore dissipates a lot of heat energy.
Reply 2
gunpowda
How does the liver help control body temperature? (GCSE purposes).

Thanks.


The metabolic reactions it's involved with, generate a lot of heat.
well, the liver and pancreas work together to adjust blood sugar level (part of homeostasis) but regarding body temperature i think it just makes urea. soz wasnt much help
Reply 4
hornblower
The liver is one of the largest internal organs of the body. It therefore dissipates a lot of heat energy.



True, but unlikely to gain many marks.

The liver is responsible for the conversion of fructose and galactose into glucose which can be used for cellular respiration. In addition, the liver can convert fat and protein into carbohydrates.
Reply 5
Ralfskini
True, but unlikely to gain many marks.

The liver is responsible for the conversion of fructose and galactose into glucose which can be used for cellular respiration. In addition, the liver can convert fat and protein into carbohydrates.


Mammals cannot convert lipid (fat) into carbohydrate. Do NOT write this. You can convert glycerol (one of the breakdown products of lipolysis) into glucose, but fatty acids cannot be converted - they are used directly as fuel by muscle (and other) cells.
Reply 6
Great. I think the safest bet is probably that it's involved in metabolic processes and exothermic reactions. Thanks everybody.
gunpowda
How does the liver help control body temperature? (GCSE purposes).

Thanks.


generally a nasty/poor question, since the liver does not directly help control body temperature so its rather controversial.

Helenia
Mammals cannot convert lipid (fat) into carbohydrate
I think you maybe partially right, and partially wrong. You cannot convert triglycerides completely into carbohydrates is true.

However, like Ralfskini mentioned:
the liver can convert fat into carbohydrates
, that is true - I think.

I think you're confused with the term "lipid(s)". Lipid is NOT defined as or is NOT JUST FAT, lipid can be correctly defined as any of a group of organic compounds, that are insoluble in water but soluble in nonpolar organic solvents. Applying this definition, lipids include, triglyceride, oils, and fats.

So, therefore I think fats can be converted into carbohydrate directly. I am not entirely sure if I'm right or not, and I may need to cross-check. Anyone else got any suggestions?
Reply 8
ResidentEvil
I think you're confused with the term "lipid(s)". Lipid is NOT defined as or is NOT JUST FAT, lipid can be correctly defined as any of a group of organic compounds, that are insoluble in water but soluble in nonpolar organic solvents. Applying this definition, lipids include, triglyceride, oils, and fats.

So, therefore I think fats can be converted into carbohydrate directly. I am not entirely sure if I'm right or not, and I may need to cross-check. Anyone else got any suggestions?


Oils and fats are triglycerides, just with differing amounts of saturation in their fatty acid chains. They are all the same thing - three fatty acid chains ester bonded to a glycerol molecule. Triglyceride (triacylglycerol, TAG) is NOT used in gluconeogenesis - I quote from my lecture notes "fatty acids are not glucogenic because mammals cannot convert acetyl CoA to glucose."

There are many many things in Biochemistry that I don't know (I couldn't describe gluconeogenesis from glycerol for you) but I do know that much.
Helenia
Oils and fats are triglycerides, just with differing amounts of saturation in their fatty acid chains. They are all the same thing - three fatty acid chains ester bonded to a glycerol molecule. Triglyceride (triacylglycerol, TAG) is NOT used in gluconeogenesis - I quote from my lecture notes "fatty acids are not glucogenic because mammals cannot convert acetyl CoA to glucose."

There are many many things in Biochemistry that I don't know (I couldn't describe gluconeogenesis from glycerol for you) but I do know that much.


hmmm looks like I got some revision to do lol. Yeah, what you said makes perfect sense now, thanks for the elaboration. Sorry, I think Ive just done too much work today, my brain has disappeared elsewhere!
In my defense, I may not have made things clear but I never imagined the fatty acid part of the triglyceride having anything to do with gluconeogenesis. I always thought the ester bonds were hydrolysed and glycerol was then phosphorylated and converted to glucose.
Reply 11
Ralfskini
In my defense, I may not have made things clear but I never imagined the fatty acid part of the triglyceride having anything to do with gluconeogenesis. I always thought the ester bonds were hydrolysed and glycerol was then phosphorylated and converted to glucose.


It is, but to say that lipids are converted to glucose is an easy way to get the examiner to take marks off you. Glycerol is only part of a lipid - the FAs are far more substantial. Sorry to be picky - it's just one of those things my Biology teacher (and lecturers here) taught me to love to hate!
Helenia
It is, but to say that lipids are converted to glucose is an easy way to get the examiner to take marks off you. Glycerol is only part of a lipid - the FAs are far more substantial. Sorry to be picky - it's just one of those things my Biology teacher (and lecturers here) taught me to love to hate!



Thanks, hopefully I'll remember that.
Reply 13
Lol...don't worry, all that complicated stuff isn't required for GCSE. To simplify the above, the liver contributes to homeostasis by converting glucose in the blood to glycogen when the blood glucose levels are too high. When the blood glucose levels are too low, the liver converts glycogen back into glucose.

The liver works with the pancreas to carry this out. The pancreas secretes the hormone insulin into the blood stream, which tells the liver to start the conversion of glucose into glycogen. This is when the blood sugar levels are too high. When the blood sugar levels are too low, the pancreas secretes glucagon into the blood stream, which tells the liver not to convert so much glucose into glucagon, and in fact make glycogen into glucose. And so the blood sugar levels can be kept constant using this rather cunning method. And that's how the liver contributes to homeostasis for GCSE, in case you were having a fit about what the hell "gluconeogenesis" was.

In response to the original question, I have no idea. Does it?
Reply 14
glance
Lol...don't worry, all that complicated stuff isn't required for GCSE. To simplify the above, the liver contributes to homeostasis by converting glucose in the blood to glycogen when the blood glucose levels are too high. When the blood glucose levels are too low, the liver converts glycogen back into glucose.

The liver works with the pancreas to carry this out. The pancreas secretes the hormone insulin into the blood stream, which tells the liver to stop the conversion of glucose into glycogen. This is when the blood sugar levels are too high. When the blood sugar levels are too low, the pancreas secretes glucagon into the blood stream, which tells the liver not to convert so much glucose into glucagon, and in fact make glycogen from glucose. And so the blood sugar levels can be kept constant using this rather cunning method. And that's how the liver contributes to homeostasis for GCSE, in case you were having a fit about what the hell "gluconeogenesis" was.

In response to the original question, I have no idea. Does it?


You've got your hormones mixed up. Insulin is secreted when blood sugar is high, yes, but it stimulates the liver to make glycogen, not stop making it. Glucagon is secreted in response to low blood sugar, and stimulates glycogen breakdown, not synthesis.

Sorry for getting over-technical on the gluconeogenesis aspect of things, but it needed to be done to correct the original incorrect statement that you can do it from lipids. You do not need to know this for GCSE - you barely need to know it for A-Level!

As for the original question, the liver is responsible partly for the body's core temperature being so high compared with atmospheric, because of all the exothermic reactions going on there. However, it is not used for fine control of temperature - that is done by sweating and vasodilation (opening blood vessels near to skin) when you are hot, and raising hairs, shivering and vasoconstriction (closing surface blood vessels, keeping blood in the core) when you are cold.
Reply 15
Helenia...you are absolutely right! Well spotted...correcting now...what the hell was I on about?!
Reply 16
Guys, i think it is a popular belief that the liver generates heat through exothermic reactions that take place, but studies have shown that the temperature of the blood in the hepatic vein is the same as the temperature in the hepatic artery - save for the usual temperature difference between veins and arteries.

The question still really hasn't been answered. Is it not a little 'flat-earth'? I don't know, i'm probably the closest thing to ignorant here :redface: :confused: .
gunpowda
How does the liver help control body temperature? (GCSE purposes).

Thanks.


Geez, all this time I thought the liver helped to regulate blood glucose levels and that was about it! Could I entertain you in a summary of what goes on there? Had to write a 2,500 word essay on the topic last semester so at leasr you can be assured I'll know what I'm talking about!
Aido
Guys, i think it is a popular belief that the liver generates heat through exothermic reactions that take place, but studies have shown that the temperature of the blood in the hepatic vein is the same as the temperature in the hepatic artery - save for the usual temperature difference between veins and arteries.

The question still really hasn't been answered. Is it not a little 'flat-earth'? I don't know, i'm probably the closest thing to ignorant here :redface: :confused: .

one post wonder
The correct reasoning would be:

1) Regulates amount of protien in the body by breaking down the protiens to urea. (de-amination) by breaking down the NH2 (amino group) in protiens.
2) Stores excess carbohydrates as GLYCOGEN.
3) Maintains a constant body temperature.
4) Breaks down hormones in the blood.

Thats all you need for GCSE.

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