Sale is in Trafford and borders Chorlton and Stretford. I don't know Sale that well to be honest, its not good for buses into town but it does have a metrolink station.
Didsbury have some massive houses but don't expect to get any house for less than £500,000 in Didsbury itself, £850,000 price tags are common. Chorlton is a bit more reasonable but even there a 3 bed terrace you won't get much change out of £300k. South Manchester property prices have gone mad.