In the new system, it is likely that offers will still be based on 3 full A-levels but since there are significant reforms to A-levels being rolled out across England and Wales, there is no way to tell what university policy is going to be as there is still one more application cycle to go through which people with the old A-levels will pass.
I suggest you keep an eye on
www.ucas.com for statements made by universities as they'll probably announce what they're going to do to accommodate these reforms. Until the ones that you want to apply to release their decisions, it's not a wise move to drop the fourth subject. It's really stupid of the universities to take their time with this to be honest, since people need to decide now whether they're taking the full A-level or not...