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    What's the actual concept behind this, the process, what is it specifically about the plasma membrane that prevents a hydrophilic molecule passing through?
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    (Original post by ArabianPhoenix)
    What's the actual concept behind this, the process, what is it specifically about the plasma membrane that prevents a hydrophilic molecule passing through?
    Hydrophilic molecules are soluble in water, not lipids. The membrane is lipid based and the middle is very hydrophobic. These won't mix, in the same way that oil and water won't. This is also why water can't pass across very well.
    I think it's something to do with charges on the molecules in that things that dissolve in water have a some kind of charge, be it full or partial and things that are insoluble don't, like fats. Charged particles therefore cannot pass across the membrane whereas uncharged can


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    (Original post by jake123254)
    Hydrophilic molecules are soluble in water, not lipids. The membrane is lipid based and the middle is very hydrophobic. These won't mix, in the same way that oil and water won't. This is also why water can't pass across very well.
    I think it's something to do with charges on the molecules in that things that dissolve in water have a some kind of charge, be it full or partial and things that are insoluble don't, like fats. Charged particles therefore cannot pass across the membrane whereas uncharged can


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    Adding onto this, solubility (I think) is determined by how well a substance can bond to a solvent.

    This includes:
    dipole-dipole interactions (inc. permanent, induced etc. etc.)
    hydrogen bonding (of O, N, and F I think)

    You wouldn't need to know it for a biology exam, I think, but that's my rambling understanding of it.
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    (Original post by XcitingStuart)
    Adding onto this, solubility (I think) is determined by how well a substance can bond to a solvent.

    This includes:
    dipole-dipole interactions (inc. permanent, induced etc. etc.)
    hydrogen bonding (of O, N, and F I think)

    You wouldn't need to know it for a biology exam, I think, but that's my rambling understanding of it.
    I'm not sure how much detail it goes into in biology either, I know for some parts of biochemistry you need to know about the different bonds holding the different structures of molecules together but I'm not sure on this part


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    (Original post by XcitingStuart)
    Adding onto this, solubility (I think) is determined by how well a substance can bond to a solvent.

    This includes:
    dipole-dipole interactions (inc. permanent, induced etc. etc.)
    hydrogen bonding (of O, N, and F I think)

    You wouldn't need to know it for a biology exam, I think, but that's my rambling understanding of it.
    It's for undergrad, but it was more for knowledge than answering a question! Thank you regardless
 
 
 
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