Oh right, aorry, I misread. Tbh, it depends where you applied. Although, you were predicted 2A*'s and A, do the requirements allow the B in Biology. You should call up the universities that you've applied to or check their website out. Im not exactly sure as your doing 4 A-levels.
Depends on where you applied. Some unis eg Manchester and Keele don't require biology at A2 if you have it at AS at a certain grade (I think a b) so if you have a predicted B at A2, it should be absolutely fine.