Darelz
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"The base sequence in the section of mRNA that codes fir one of the amino acids in haemoglobin has the codon GAA.
In individuals who have sickle cell anaemia, this codon is changed from GAA to GUA.
If this disease were to be passed on by inheritance, suggest which of the following is more likely to be true, and explain your answer:
i.- There has been a mistake during transcription, where the DNA code is copied to form mRNA.
ii- The mistake was made during DNA replication where the DNA is copied to form new DNA molecules before cell division."

If it's inherited then they must have some sort of genetic issue inherited from their parents, not a random error or some new mutation? I don't know, I'm really stuck on this, it's not really like anything we did in class. Can you please explain how I work this out?
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hknobody
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ii. is true

mRNA do not pass on to next generation. DNA do, error during DNA replication in cells that produce gametes can be passed on to next generation.
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Darelz
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Thanks!
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