In drug therapy (for schizophrenia) do atypical drugs BLOCK dopamine and serotonin?Watch
Can anyone explain this\/
For the past 10 years or so doctors have talked about two different groups of antipsychotics:
‘Typical’ - the older drugs
‘Atypical’ - the newer drugs
Recent large independent research studies - not paid for by the drug companies – suggest that the new drugs are not really different – but are, in some situations, easier to use.
Medications termed antipsychotics reduce symptoms such as hallucinations and delusions through blocking the dopamine receptor D2
The "dopamine hypothesis" has been the main theory regarding the cause of the symptoms of schizophrenia. Researchers believe that many of the symptoms of schizophrenia are a result of excess of dopamine in the brain. Anti psychotic medications block dopamine transmission and are used to treat and improve the symptoms of schizophrenia.
New theories suggest that the neurotransmitter serotonin may also play a role in causing the symptoms of schizophrenia. Some anti psychotic medications treat symptoms of schizophrenia by blocking dopamine and serotonin transmissions. Many patients who have not been helped by "dopamine only” medications have been helped by medications that affect both dopamine and serotonin transmissions, such as Clozaril, Risperdal and Zyprexa.