lymphocytes and neutrophils

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HanaBhatti
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what are the differences between them?
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anosmianAcrimony
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One main difference that I've been able to find is that neutrophils only take part in innate immunity - they migrate to sites of damage and infection and deal with microbes generically. Whatever the pathogen is, a neutrophil will deal with it in basically the same way, mostly through phagocytosis.

Lymphocytes seem to be a broader category of cells that includes natural killer cells, T cells, and B cells. Natural killer cells' job is to detect heavily stressed or virally infected cells and release factors that causes them to apoptose. This is a form of innate immunity, because they don't need antibodies to detect the cells. They are also involved in adaptive immunity, as they can recognise antigens they have previously encountered.

T cells also appear to be an umbrella term for a group of different cells, but in general, they effect adaptive immunity, killing antibody-marked species, helping other immune cells through chemical signals, and storing memory of past infections.

B cells each present a certain structure of antibody on their surface. When an antigen comes along that binds to those antibodies, the cell will begin to divide and to produce many more antibodies of that structure, and will also attempt to fine-tune the antibodies' structure to bind the antigen more tightly. The antibodies then circulate the body, neutralising the antigen and recruiting other immune cells to fight the antigen. This is obviously a part of the adaptive immune system.

I hope that helps. Feel free to ask question if anything isn't clear. I'm also revising this sort of stuff at the moment.
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HanaBhatti
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#3
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(Original post by anosmianAcrimony)
One main difference that I've been able to find is that neutrophils only take part in innate immunity - they migrate to sites of damage and infection and deal with microbes generically. Whatever the pathogen is, a neutrophil will deal with it in basically the same way, mostly through phagocytosis.

Lymphocytes seem to be a broader category of cells that includes natural killer cells, T cells, and B cells. Natural killer cells' job is to detect heavily stressed or virally infected cells and release factors that causes them to apoptose. This is a form of innate immunity, because they don't need antibodies to detect the cells. They are also involved in adaptive immunity, as they can recognise antigens they have previously encountered.

T cells also appear to be an umbrella term for a group of different cells, but in general, they effect adaptive immunity, killing antibody-marked species, helping other immune cells through chemical signals, and storing memory of past infections.

B cells each present a certain structure of antibody on their surface. When an antigen comes along that binds to those antibodies, the cell will begin to divide and to produce many more antibodies of that structure, and will also attempt to fine-tune the antibodies' structure to bind the antigen more tightly. The antibodies then circulate the body, neutralising the antigen and recruiting other immune cells to fight the antigen. This is obviously a part of the adaptive immune system.

I hope that helps. Feel free to ask question if anything isn't clear. I'm also revising this sort of stuff at the moment.
thank you so much
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