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    How does the secondary immune response work which makes the second response Faster than the first response?
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    (Original post by Jennifer50)
    How does the secondary immune response work which makes the second response Faster than the first response?
    Once you have been exposed to the pathogen, your body has already produced memory B cells, memory helper T cells and memory cytotoxic T cells and there may also already be antibodies which are specific to the pathogen present in the serum. As such, when your body encounters the same pathogen again, there will be many more helper T cells which will secrete more cytokines much more quickly, activating memory B cells which will differentiate into plasma cells and produce more antibodies in a much shorter time and also memory cytotoxic T cells which will differentiate into cytotoxic T cells more quickly and destroy the pathogen more quickly. Essentially, the primary response is slow because it takes time for helper T cells to proliferate and activate B cells and cytotoxic T cells and it takes time for these cells to proliferate and be present in sufficient numbers to deal with the infection. After the primary response, there are many memory cells which will proliferate and differentiate much more quickly and so sufficient numbers of immunological cells will be present in a much shorter time to deal with the infection - usually before symptoms appear. There are also long-term plasma cells which will continue to produce antibodies in the blood long after the infection has been fought off and so these antibodies in the serum will also provide some protection against infection.
 
 
 
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