Hey there! Sign in to join this conversationNew here? Join for free
    • Thread Starter
    Offline

    1
    ReputationRep:
    What is a basal channel? Apparently it's found in the proximal convoluted tubule and it helps with selective re-absorption of glomeruler filtrate. How does it help?
    Offline

    13
    ReputationRep:
    (Original post by Banana ice-cream)
    What is a basal channel? Apparently it's found in the proximal convoluted tubule and it helps with selective re-absorption of glomeruler filtrate. How does it help?
    A basal channel is any channel in the basolateral membrane, for example the K+ channel which helps to prevent K+ buildup in the cell due to the Na+/K+-ATPase. They're found throughout the kidney but the PCT does a lot of the reabsorption so there will be lots of basal channels. It will help with making concentration gradients and you can reabsorb certain things depending on what concentration gradients you have
    • Thread Starter
    Offline

    1
    ReputationRep:
    (Original post by Gaiaphage)
    A basal channel is any channel in the basolateral membrane, for example the K+ channel which helps to prevent K+ buildup in the cell due to the Na+/K+-ATPase. They're found throughout the kidney but the PCT does a lot of the reabsorption so there will be lots of basal channels. It will help with making concentration gradients and you can reabsorb certain things depending on what concentration gradients you have
    Thanx. What's the basolateral membrane? So it's basically an ion pump? Or does it just help with facilitated diffusion?
    Offline

    13
    ReputationRep:
    (Original post by Banana ice-cream)
    Thanx. What's the basolateral membrane? So it's basically an ion pump? Or does it just help with facilitated diffusion?
    Ah sorry, I didn't see that this was A level. The renal tubule (where the filtrate from the Bowman's capsule goes) is separated from the interstitial fluid of the kidney by a layer of cells, and there are different channels on each side. The side of the cell that's in contact with the tubule is called the tubular membrane, and the side of the cell that's in contact with the interstitial fluid is called the basolateral membrane. So channels on the basolateral membrane will move things from the cell into the interstitium and vice versa, which is effectively back into the bloodstream.

    Technically, channels and ion pumps are different (channels are passive, pumps are active) so yes it just helps with facilitated diffusion.

    I'm a first year medic with exams coming up soon and I'm currently revising the kidney which is where I got all this from, you won't need to know it for A level! But hopefully it'll help you understand it which is always helpful
 
 
 
  • See more of what you like on The Student Room

    You can personalise what you see on TSR. Tell us a little about yourself to get started.

  • Poll
    Has a teacher ever helped you cheat?
  • See more of what you like on The Student Room

    You can personalise what you see on TSR. Tell us a little about yourself to get started.

  • The Student Room, Get Revising and Marked by Teachers are trading names of The Student Room Group Ltd.

    Register Number: 04666380 (England and Wales), VAT No. 806 8067 22 Registered Office: International House, Queens Road, Brighton, BN1 3XE

    Write a reply...
    Reply
    Hide
    Reputation gems: You get these gems as you gain rep from other members for making good contributions and giving helpful advice.