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Last edited by matilda12345; 10-04-2016 at 15:09.
- 10-04-2016 14:51
- 10-04-2016 14:54
Don't take my word for it but I would imagine that the carbon dioxide reacts with the water in tissues to form a weak carbonic acid which then dissociates into hydrogen carbonate ions and hydrogen ions
- 10-04-2016 15:05
Carbon dioxide + water --> H2CO3 (carbonic acid)
Carbonic acid then disassociates into H+ ions and HCO3-.
Most of the Carbon dioxide is transported in the cytoplasm of the red blood cells as hydrogencarbonate ions. In the body tissues, there is a high concentration of CO2 and Carbonic anhydrase to form carbonic acid. Which then disassociates.
- 10-04-2016 17:05
This correct. 93% of blood CO2 is in the form of HCO3- and a small amount is combined with Hb as carboxyhaemoglobin.
The existence of HCO3- in the blood is very important as it functions as a buffer which stabilises blood pH.
The thing about 2,3 DPG however is an allosteric effect which favours O2 unloading at lower pO2.