Hey there! Sign in to join this conversationNew here? Join for free
    • Thread Starter
    Offline

    14
    ReputationRep:
    Hi guys!

    Can someone give me a bit of help. I've got to do a 1500 word essay on the mode of action of paracetamol on the brain. Can someone give me a start, I'm an AS student so I'm just lost.


    Thanks!
    Offline

    13
    ReputationRep:
    This seems like a really tough thing to ask for at AS-level, particularly as no-one really knows how paracetamol works. These issues are likely to be covered in academic papers but you probably won't have access to many of these. You might want to look at:

    http://www.slideshare.net/aclaesson/...share-39192733
    http://onlinelibrary.wiley.com/enhan...pt.2005.09.009

    Note that paracetamol (probably) has both peripheral and central (i.e. the brain) effects... it sounds as if your essay should only be focussing on the latter.

    Tough !!
    Offline

    12
    ReputationRep:
    Mirror what the above poster has said.....does anyone actually know?! Have you been given this or have you chosen it as a title?!
    • Thread Starter
    Offline

    14
    ReputationRep:
    I've chosen this as my title after emailing my tutor to changing it, Erm, is there a more straightforward drug which has a more straightforward mode of action on the brain?
    Offline

    12
    ReputationRep:
    Off the top of my head SSRIs, which are first line antidepressants, would be easier. Or the antipsychotics. If you want to stick with pain relief though then maybe ibuprofen (NSAID) or morphine (opioid) would both be better than paracetomol. There is a lot of scope with the psychiatric drugs especially, but with 1500 words you could get an essay out of any of the ones i mentioned
    Offline

    18
    ReputationRep:
    Agree with MonteCristo, choosing to write about paracetamol would make your life difficult

    Also agree with Zakadoh - opioids (e.g. morphine) are good to talk about in terms of painkillers, but IMO antipsychotics (especially the comparing difference between the first and second generation antipsychotics) would also be good to talk about in terms of different neuronal pathways and the drugs' efficacy and safety.
    • Thread Starter
    Offline

    14
    ReputationRep:
    (Original post by Zakadoh)
    Off the top of my head SSRIs, which are first line antidepressants, would be easier. Or the antipsychotics. If you want to stick with pain relief though then maybe ibuprofen (NSAID) or morphine (opioid) would both be better than paracetamol. There is a lot of scope with the psychiatric drugs especially, but with 1500 words you could get an essay out of any of the ones i mentioned
    Thank you so much! Erm, so if i email my tutor ask to do morphine instead, will morphine be easier to write about and more straightforward in terms of brain and the pharmacology behind it?

    I've probably bugged you enough but could you send me a link to start off research for the mechanism for morphine?

    Thanks again, you're a lifesaver!
    Offline

    12
    ReputationRep:
    (Original post by Loyale)
    Thank you so much! Erm, so if i email my tutor ask to do morphine instead, will morphine be easier to write about and more straightforward in terms of brain and the pharmacology behind it?

    I've probably bugged you enough but could you send me a link to start off research for the mechanism for morphine?

    Thanks again, you're a lifesaver!
    Haha! Morphine will definitelty be easier. Im not gunna give you a link though matey....not being harsh, but 5 minutes on google and you can do that. If you wanna be a med student youre gunna be doing a lot of that! Lol
 
 
 
Poll
Do you agree with the PM's proposal to cut tuition fees for some courses?

The Student Room, Get Revising and Marked by Teachers are trading names of The Student Room Group Ltd.

Register Number: 04666380 (England and Wales), VAT No. 806 8067 22 Registered Office: International House, Queens Road, Brighton, BN1 3XE

Write a reply...
Reply
Hide
Reputation gems: You get these gems as you gain rep from other members for making good contributions and giving helpful advice.