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Is it true that mixing sedatives with alcohol can be 'dead'ly Watch

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    i find that quite strange. So an explanation would be nice, why would alcohol do that? people can take lets say over 100mg of valium and be fine, why would it be different if you thorw in alcohol to the mix. its fascinating.
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    I would imagine that in cases where large amounts of alcohol are concerned, such as when enough is consumed to make you vomit, the danger would be that a person under the influence of sedatives would be unable to clear the vomit from the mouth and throat.
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    (Original post by Ciel.)
    i find that quite strange. So an explanation would be nice, why would alcohol do that? people can take lets say over 100mg of valium and be fine, why would it be different if you thorw in alcohol to the mix. its fascinating.
    Alcohol and certain sedatives/hypnotics, e.g. benzodiazepines have synergistic effect, in that they both act on the same receptor (GABAA), one consequence of which is respiratory depression, which, if severe enough, can be fatal.
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    why would you want to mix benzos and alcohol anyway...most people can sleep on alcohol and it would muddy the high of the downers.
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    (Original post by thegodofgod)
    Alcohol and certain sedatives/hypnotics, e.g. benzodiazepines have synergistic effect, in that they both act on the same receptor (GABAA), one consequence of which is respiratory depression, which, if severe enough, can be fatal.
    if they act on the same receptor then why are they ONLY deadly when u mix them. and not on their own, evne in a massive dose.?
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    (Original post by Ciel.)
    if they act on the same receptor then why are they ONLY deadly when u mix them. and not on their own, evne in a massive dose.?
    They are...

    Anything at a crazily high dose will kill you.

    Have you heard of a very famous toxicologist called Paracelsus? He effectively said that the dose makes the poison, i.e. everything is a poison, but it is the dose (quantity) that determines whether it is safe or toxic.
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    (Original post by thegodofgod)
    They are...

    Anything at a crazily high dose will kill you.

    Have you heard of a very famous toxicologist called Paracelsus? He effectively said that the dose makes the poison, i.e. everything is a poison, but it is the dose (quantity) that determines whether it is safe or toxic.
    but usually a crazilyy high dose will just make you sick BEFORE it kills you. Depressing stuff
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    (Original post by Ciel.)
    if they act on the same receptor then why are they ONLY deadly when u mix them. and not on their own, evne in a massive dose.?
    Erm, perfectly feasible for people to die from either benzo or alcohol OD, though usually because of the aforementioned effect of not being able to protect their airway. Not something to experiment with, anyway!

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    (Original post by Helenia)
    Erm, perfectly feasible for people to die from either benzo or alcohol OD, though usually because of the aforementioned effect of not being able to protect their airway. Not something to experiment with, anyway!

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    ah, hahaha how unpleasant!
 
 
 
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