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How a mutation in the genome would lead to loss of virulence of the virus???
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(Original post by Hazel99)
Influenza
Influenza
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(Original post by AortaStudyMore)
Any number of mutations could cause this, the ones that spring to mind would be mutations in the genes that produce haemagglutinin and neuraminidase (the glycoproteins that allow the virus to enter and leave cells), or mutations in the genes that are involved in RNA replication. You get the idea. Basically any mutation in a gene that is going to prevent the virus from making you ill, such as being unable to replicate or enter the target tissue
Any number of mutations could cause this, the ones that spring to mind would be mutations in the genes that produce haemagglutinin and neuraminidase (the glycoproteins that allow the virus to enter and leave cells), or mutations in the genes that are involved in RNA replication. You get the idea. Basically any mutation in a gene that is going to prevent the virus from making you ill, such as being unable to replicate or enter the target tissue
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