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    Hi, I was just making some notes on Nucliec Acids for my Bio class, and was wondering if Phosphodiester bonds were covalent bonds. In my CCEA revisionguide, it says how Sugar-Phosphate baackbone of a DNA Molecule is held together by covalent bonds. However, on A Level Notes website it says 'Many nucleotides joined together in this way [Phosphodiester linkage] make a repeating Sugar-Phosphate 'backbone' out of which the organic bases project.


    So I was wondering if Phosphodiester Bonds are infact covalent bonds?.
    Thank you.

    Revisionlad
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    (Original post by revisionlad)
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    Hi there,

    Phosphodiester Bonds are indeed strong covalent bonds between the Phosphate group and the Deoxyribose (Pentose) Sugar via 2 ester bonds.
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    Yes you are correct.

    The nucleotides within each strand are held together by the phosphodiester bonds between the 5' carbon of one nucleotide and the 3 ' carbon of the adjacent nucleotide. These strong covalent bonds form the the glue that holds the sugar/phosphate backbone together and thus act to keep each strand together.
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    (Original post by AshEntropy)
    Hi there,

    Phosphodiester Bonds are indeed strong covalent bonds between the Phosphate group and the Deoxyribose (Pentose) Sugar via 2 ester bonds.
    Thanking you
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    (Original post by sameehaiqbal)
    Yes you are correct.

    The nucleotides within each strand are held together by the phosphodiester bonds between the 5' carbon of one nucleotide and the 3 ' carbon of the adjacent nucleotide. These strong covalent bonds form the the glue that holds the sugar/phosphate backbone together and thus act to keep each strand together.
    Thank you very much
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    (Original post by revisionlad)
    Thanking you
    No problem
 
 
 
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