revisionlad
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Hi, I was just making some notes on Nucliec Acids for my Bio class, and was wondering if Phosphodiester bonds were covalent bonds. In my CCEA revisionguide, it says how Sugar-Phosphate baackbone of a DNA Molecule is held together by covalent bonds. However, on A Level Notes website it says 'Many nucleotides joined together in this way [Phosphodiester linkage] make a repeating Sugar-Phosphate 'backbone' out of which the organic bases project.


So I was wondering if Phosphodiester Bonds are infact covalent bonds?.
Thank you.

Revisionlad
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2384911
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(Original post by revisionlad)
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Hi there,

Phosphodiester Bonds are indeed strong covalent bonds between the Phosphate group and the Deoxyribose (Pentose) Sugar via 2 ester bonds.
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username1842595
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Yes you are correct.

The nucleotides within each strand are held together by the phosphodiester bonds between the 5' carbon of one nucleotide and the 3 ' carbon of the adjacent nucleotide. These strong covalent bonds form the the glue that holds the sugar/phosphate backbone together and thus act to keep each strand together.
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revisionlad
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(Original post by AshEntropy)
Hi there,

Phosphodiester Bonds are indeed strong covalent bonds between the Phosphate group and the Deoxyribose (Pentose) Sugar via 2 ester bonds.
Thanking you
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revisionlad
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(Original post by sameehaiqbal)
Yes you are correct.

The nucleotides within each strand are held together by the phosphodiester bonds between the 5' carbon of one nucleotide and the 3 ' carbon of the adjacent nucleotide. These strong covalent bonds form the the glue that holds the sugar/phosphate backbone together and thus act to keep each strand together.
Thank you very much
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2384911
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(Original post by revisionlad)
Thanking you
No problem
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