Why do hydrophobic interactions increase with an elevated temperature?

For example in amino acids, some proteins have an extreme resistance to heat as a result of the attractions of non polar side chains of amino acids getting stronger. Why does this increased attraction occur?

Reply 1

WhoDaresWins

Original post by HouseOfRichman

Have you heard of zwitterions? There's a strong attraction between the positive ions and the negative ions so amino acids have a high melting point.

(edited 7 years ago)

Reply 2

username1863871

I have heard of zwitterions, though I think what I meant can be seen in this article: http://www.jbc.org/content/237/8/2506.full.pdf
In a nutshell, the formation of the bonds between non-polar side chains is unusually endothermic and therefore, increasing the temperature supplied to the system of such a reaction causes the strength of the bonds to increase :smile: