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Making aspirin from salicylic acid Watch

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    Can aspirin still be made by reacting salicylic acid with ethanoic acid in esterification? Does the OH on salicylic act as an alcohol or not as I found out that salicylic acid normally reacts with ethanoic anhydride to form aspirin...

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    Drugs are haram.
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    (Original post by coconut64)
    Can aspirin still be made by reacting salicylic acid with ethanoic acid in esterification? Does the OH on salicylic act as an alcohol or not as I found out that salicylic acid normally reacts with ethanoic anhydride to form aspirin...

    Thanks
    Dunno but Sh*t man you have a drug lab? Hit me up if you know how to cook blue meth...It's for a friend
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    The OH attached to benzene ring is actually a phenol group which behaves differently. Not totally sure about your specific question honestly.
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    (Original post by black1blade)
    The OH attached to benzene ring is actually a phenol group which behaves differently. Not totally sure about your specific question honestly.
    Sorry about that. The question asks you to suggest a reaction to make aspirin from salicyclic acid. The answer would be reacting salicylic acid with ethanoic anhydride but I thought salicylic acid can behave like an alcohol. So phenol never behaves like an alcohol ? Thanks
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    (Original post by coconut64)
    Sorry about that. The question asks you to suggest a reaction to make aspirin from salicyclic acid. The answer would be reacting salicylic acid with ethanoic anhydride but I thought salicylic acid can behave like an alcohol. So phenol never behaves like an alcohol ? Thanks
    I don't think so at least I can't think of any cases in which it would. I'm pretty sure we do a lot more on the chemistry of benzene rings in a2 chemistry which will hopefully explain the difference in properties. But yeah I know for sure that phenol is much more acidic than alcohol group (phenol can make salts with alkalis but not not carbonates) and phenols can't be oxidized under reflux by potassium dichromate.
 
 
 
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