Help with Hummoral response/cell mediated response
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teenhorrorstory
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Hey guys. I have a lot of trouble remembering the steps in the Hummoral response, i.e. T helper Activation & The effector stage and the Cell mediated response because they all seem similar to me so I confuse them. Does anyway have a good way of remembering the processes??
Many thanks
Many thanks
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teenhorrorstory
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LennyBicknel
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If you're a visual learner, doing a big flow chart of the different steps has helped me out.
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Gerry-Atricks
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I just remember humoral response first
-t helper activation then effector stage, imagine it like in chem you need an activation energy to start a reaction so here you need to activate t helper first off so t helper activation starts by a pathogen with antigen on surface engulfed by macrophage and antigen is presented on MHC`s ( major histocompatibility complexes) to form an APC (antigen presenting cell), from here the APC binds with the T helper cells, activating it and forming a clone of t memory cells and active t helper cells as end products.
In effector stage, APC produced ( i should make clear, initally at this stage b cell binds to antigen, b cell engulfs it and destroys into fragments which are then engulfed by macrophage to make APC)
So now we use the activated t helper cell to bind with APC, releasing cytokines which stimulate b cell, b cell now divides to give a clone of b memory cells and b effector cell clones- effector differentiate into plasma cells which then release antibodies.
Cell mediated immune response occurs when a virus/pathogen is inside a host cell so humoral not very effective, so here, bacterium infects cell, cell presents antigens on MHCs forming APC, this binds with the complementary t killer cells, and using cytokines from t helper cells, the t killer is stimulated to form a clone of t memory and active t killer cells, active t killer( rather aptly named) do the killing of the infected cell, they bind to the APC and release chemicals that cause cell lysis, killing the infected cell
-t helper activation then effector stage, imagine it like in chem you need an activation energy to start a reaction so here you need to activate t helper first off so t helper activation starts by a pathogen with antigen on surface engulfed by macrophage and antigen is presented on MHC`s ( major histocompatibility complexes) to form an APC (antigen presenting cell), from here the APC binds with the T helper cells, activating it and forming a clone of t memory cells and active t helper cells as end products.
In effector stage, APC produced ( i should make clear, initally at this stage b cell binds to antigen, b cell engulfs it and destroys into fragments which are then engulfed by macrophage to make APC)
So now we use the activated t helper cell to bind with APC, releasing cytokines which stimulate b cell, b cell now divides to give a clone of b memory cells and b effector cell clones- effector differentiate into plasma cells which then release antibodies.
Cell mediated immune response occurs when a virus/pathogen is inside a host cell so humoral not very effective, so here, bacterium infects cell, cell presents antigens on MHCs forming APC, this binds with the complementary t killer cells, and using cytokines from t helper cells, the t killer is stimulated to form a clone of t memory and active t killer cells, active t killer( rather aptly named) do the killing of the infected cell, they bind to the APC and release chemicals that cause cell lysis, killing the infected cell
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Gerry-Atricks
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(Original post by teenhorrorstory)
Hey guys. I have a lot of trouble remembering the steps in the Hummoral response, i.e. T helper Activation & The effector stage and the Cell mediated response because they all seem similar to me so I confuse them. Does anyway have a good way of remembering the processes??
Many thanks
Hey guys. I have a lot of trouble remembering the steps in the Hummoral response, i.e. T helper Activation & The effector stage and the Cell mediated response because they all seem similar to me so I confuse them. Does anyway have a good way of remembering the processes??
Many thanks
(Original post by LennyBicknel)
If you're a visual learner, doing a big flow chart of the different steps has helped me out.
If you're a visual learner, doing a big flow chart of the different steps has helped me out.
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Gerry-Atricks
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#6
(Original post by teenhorrorstory)
Hey guys. I have a lot of trouble remembering the steps in the Hummoral response, i.e. T helper Activation & The effector stage and the Cell mediated response because they all seem similar to me so I confuse them. Does anyway have a good way of remembering the processes??
Many thanks
Hey guys. I have a lot of trouble remembering the steps in the Hummoral response, i.e. T helper Activation & The effector stage and the Cell mediated response because they all seem similar to me so I confuse them. Does anyway have a good way of remembering the processes??
Many thanks
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