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Why is muscle contraction irreversible in vitro? What affects this the most? Watch

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    Hi!
    I know that muscle contraction is irreversible in vitro, but I was wondering why exactly this happens and what has the most profound effect on a muscle contraction? Whether the lack of a constant supply of ATP, or the Calcium level, or perhaps another factor would have the most significant effect on a muscle's ability to contract.

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    In vitro? or in vivo?
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    (Original post by QuentinM)
    In vitro? or in vivo?
    In vitro
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    Ah ok. I see a similar question was asked yesterday about this-probably by you as well.

    Most of the answers mention a lack of ATP as the main reason. ATP is needed to free the myosin heads, so i'd agree with this. Without enough ATP being produced, the muscle could become paralysed in place, with the myosin heads stuck to the tropomyosin binding sites.
 
 
 
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