Enzymes and pHWatch this thread
what do the OH- ions and H+ ions do to the structure/bonds in the tertiary structure
More specifically depending on an enzymes location in the bosy the side chains have more Carboxyl or Amine functional groups. Depending on this the presence of more H+ or OH- will effect the pKa of the enzyme. Different enzymes work optimally at a different pKa so changing this effects the rate of reaction of the enzyme
- Above and below the optimum pH, the H+ and OH- ions in acids and alkalis can break the ionic and hydrogen bonds that hold the enzymes tertiary structure together. This makes the active site change shape, so the enzyme is denatured.