Biology: Transcription of DNA for polypeptide synthesis

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Holly6400
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I wanted to ask about the enzymes that work in transcription. So obviously at the start, the DNA helix is 'unzipped'. Is the enzyme that does this DNA helicase?? and when the strands join back up, is that done by DNA polymerase or are these 2 enzymes only for DNA replication?
Thank you!
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lcschofield
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There’s also DNA gyrase which uncoils the DNA strand and DNA ligase which joins the fragments of the antilagging strand. They’re also the ones you need to know for OCRA
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Holly6400
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(Original post by lcschofield)
There’s also DNA gyrase which uncoils the DNA strand and DNA ligase which joins the fragments of the antilagging strand. They’re also the ones you need to know for OCRA
Ah okay, thank you! Are the ones I've mentioned also correct?
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lcschofield
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Yeah they are!!
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Holly6400
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Great, thank you so much for your help!!
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username2858058
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RNA polymerase II in eukaryotes
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Holly6400
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(Original post by faith 101)
RNA polymerase II in eukaryotes
Ah okay, what does that do during transcription? I struggle grasping this unit for some reason :banghead:
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username2858058
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(Original post by Holly6400)
Ah okay, what does that do during transcription? I struggle grasping this unit for some reason :banghead:
The above posts are referring to dna replication, not transcription.. i think

Transcription is about the synthesis of mRNA

This involves RNA polymerase II in eukaroytes. It does a lot! It basically interacts with transcription factors to pry apart DNA and then synthesises the mRNA transcript. It also does proofreading of the mRNA to ensure the right sequence is incorporated

I cant remember much sorry. This is off the top of ma head
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