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    Hi,

    I understand that when acetylcholine binds to Sodium ion protein channels on the postsynaptic membrane of a synapse, this causes the Na+ channels to open and Sodium ions are transported through via facilitated diffusion. Where do these Sodium ions come from? Are they just occupying the space in the synaptic cleft or is there another reason?

    Thanks!
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    (Original post by DhylanP - CRGS)
    Hi,

    I understand that when acetylcholine binds to Sodium ion protein channels on the postsynaptic membrane of a synapse, this causes the Na+ channels to open and Sodium ions are transported through via facilitated diffusion. Where do these Sodium ions come from? Are they just occupying the space in the synaptic cleft or is there another reason?

    Thanks!
    The sodium ions are outside of a neuron (extracellular space). In an interaction with potassium ions, which are inside of the a neuron (intracellular space), an action potential is caused. This action potential goes on till the synapses. An action potential is in motion by transfering the sodium ions into the inside of the neuron and vice versa the potassium ions outside of it. (via sodium and potassium channels).
 
 
 
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