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Epistasis

Hi all,

Have been debating the answer to this question as the wording is very dodgy - can someone give me a hand? Many thanks!

For two mutations, A and B, what does “A is epistatic to B” literally mean?

a. The double mutant AB has the same phenotype as A
b. Gene B acts downstream of A
c. Gene A inhibits gene B
d. All of the above

Many thanks!

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