Can someone explain to me the Bohr effect?Watch
Can someone explain to me why does this happen and is there more to the Bohr effect?
The reason (you ask why) for the Bohr effect is that it shifts the graph of pO2 (partial pressure of oxygen) on the x axis against %age saturation of haemoglobin [Hb] with O2 on the y axis to the right.
As you will know, this graph has a sigmoid shape, either cos some imaginary creature called God so designed it OR cos it is a miraculous feat of nature and evolution [depending on whether you believe in non-existent contraptions created by man OR the logical, evidence-based scientific principles originally laid down by Darwin).
This sigmoid shape means that at low pO2 (in tissues) a very large amount of O2 is released and at high pO2 (in lungs), a very high amount of O2 is attached to Hb.
When the graph moves to the right [=Bohr effect; same thing happens with high chloride ion levels [try to work out why - bit of chemistry - sciences work together!]], if you look at the two graphs (same axes: normal plot and Bohr effect plot - I shall try and upload pic for u if TSR allows today - TSR is a bit moody like giggling schoolgirls! sorry), you will see that EVEN MORE O2 is released at the tissues (where O2 is low [so towards the left of the graph] and where CO2 is high [which has produced this Bohr shift]) which is of course what you need [there is an oxygen deficit, with me?], cos these e.g,. muscles that are working like mad to do the 54 miles of cycling (have you done the London-Brighton bike ride b4? - join me next year - BUT BE CAREFUL you will need to pull your socks up man! - it is not easy I can assure you! ) are producing more CO2 leading to the Bohr shift yeah?).
Watch this space as I try to upload pic!
Best of luck in remaining exams!
Look at curve on right cos pH goes down due to:-
CO2 + H2O = H2CO3
H2CO3 ------> H+ + HCO3-
when CO2 is high