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    Decent paper! Here's my mark scheme - Rehaan

    Q1 Osteoblast - Feedback
    1.1
    Positive feedback as more insulin produced
    Which stimulates more osteoblasts (so deviates further from norm)
    1.2
    Acidic so more H+ which alter (polarity of) tertiarty structure
    So active as complementary to receptors on membrane of Beta cells.

    Q2 Rhiz B Cell Question
    2.1
    Spearman's Rank as looking for correlation.
    2.2
    The data shows conclusion as positive correlation.
    But range for each point
    Small sample/only 15
    Unaware of effects overtime.
    Unaware if healthy or cancer specifically killed.
    2.3
    1.8 x 10^8
    2.4
    Non functional NOCHAT1 so non-functional transcription factor
    Mutated CD20/non-functional CD20 on membrane
    So less Rhizo(?) binds so less death of B cells (as less destroyed)

    Q3
    CANT REMEMBER

    Q4

    Q5 (Was this the polar body one?)
    a in both boxes.
    33 mitochondria

    Why is this treatement effective (removing nucleus and putting mitochondria disease cell body into egg).
    Prevents inheritance as no nucleus
    So when fertilised by sperm zygote will not have disease as no nucleus from mother's egg/may not even form successful zygote for that egg.

    Q6 Ammonia
    6.1
    Microgram - small concentration of ammonia as bacteria
    Per gram - allows for comparisons as per gram (so different initial masses accounted for)
    6.2
    4/5. something?

    Graph shows more mRNA yet may not be equal to growth of bacteria. Why?
    Not all mRNA translated
    So not all secreted into soil as not all produced
    So may not take up nitrates from soil
    Nitrates used for growth. So cannot say that mRNA = growth.

    Q7 Haemocytometer

    5.8 something

    Why bottom red blood cells counted?
    Standardised readings
    Bottom of one forms another square so accounted for.

    ESSAY:

    The importance of the control of movement in cells and organisms.

    Calcium ions controlling muscle movement
    Spindle fibres controlling chromosome movement
    Carrier protein specificity controlling movement across membranes
    Insulin controlling movement of glucose into cells
    Muscle tissue in arteries controlling movement of blood in vessels
    Control of movement of sodium and potassium ions in nerves by voltage gated channels
    Enzymes in controlling cell cycle (off spec)
    Regulation of gene expression and epigenetics
    Control by tumour suppressor genes and protooncogene in tumour formation
    IAA in controlling tropisms
    Receptors and controlling heart rate as faster movement of blood etc

    The importance of interactions
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    Ugly Application questions as usual but in my opinion, beautiful essay questions.
    Posted on the TSR App. Download from Apple or Google Play
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    (Original post by GCSEStudent903)
    Osteoblast - Feedback
    1.1
    Positive feedback as more insulin produced
    Which stimulates more osteoblasts (so deviates further from norm)
    1.2
    pH alters
    Omg i said that for 1.1 but for 1.2 i mentioned about H+ increasing so it activates it when it enters into the protein by active transport loll i was just waffling
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    I didn't get to finish my essay 😭 Thanks to stupid application questions taking my time
    Posted on the TSR App. Download from Apple or Google Play
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    Is this enough for interaction in cells

    *DIABETS (ALPHA CELLSS) (I INCLUDED THE IDEA OF PREGNANT WOMEN HAVING GLUCOSE IN URINE AND TEST FOR DIABETES)
    * EPITELIAL CELLS (ABSORPTION AND I MENTIONED KIDNEYS)
    * COURTSHIP BEHAVIOUR
    * TAXONOMY
    * XYLEM
    *PHLOEM
    * TCELLS AND BCELLS ( I MENTIONED ABOUT SCID)
    i ran out of time 😭😭😭
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    What were the two essay titles?
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    (Original post by pploveash)
    Is this enough for interaction in cells

    *DIABETS (ALPHA CELLSS) (I INCLUDED THE IDEA OF PREGNANT WOMEN HAVING GLUCOSE IN URINE AND TEST FOR DIABETES)
    * EPITELIAL CELLS (ABSORPTION AND I MENTIONED KIDNEYS)
    * COURTSHIP BEHAVIOUR
    * TAXONOMY
    * XYLEM
    *PHLOEM
    * TCELLS AND BCELLS ( I MENTIONED ABOUT SCID)
    i ran out of time 😭😭😭
    Sucession i mentioned
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    (Original post by pploveash)
    Is this enough for interaction in cells

    *DIABETS (ALPHA CELLSS) (I INCLUDED THE IDEA OF PREGNANT WOMEN HAVING GLUCOSE IN URINE AND TEST FOR DIABETES)
    * EPITELIAL CELLS (ABSORPTION AND I MENTIONED KIDNEYS)
    * COURTSHIP BEHAVIOUR
    * TAXONOMY
    * XYLEM
    *PHLOEM
    * TCELLS AND BCELLS ( I MENTIONED ABOUT SCID)
    i ran out of time 😭😭😭
    4 developed topics is all you need. I talked about diabetes, courtship behavior, succession, T cells and B cells, mycorrizhae
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    (Original post by pploveash)
    Is this enough for interaction in cells

    *DIABETS (ALPHA CELLSS) (I INCLUDED THE IDEA OF PREGNANT WOMEN HAVING GLUCOSE IN URINE AND TEST FOR DIABETES)
    * EPITELIAL CELLS (ABSORPTION AND I MENTIONED KIDNEYS)
    * COURTSHIP BEHAVIOUR
    * TAXONOMY
    * XYLEM
    *PHLOEM
    * TCELLS AND BCELLS ( I MENTIONED ABOUT SCID)
    i ran out of time 😭😭😭
    I also mentioned sucession
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    I got 33 for number of mitochondria in calculation
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    Did you just multiply by 200 (or whatever the dilution was) for that calculation
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    Why use micrometers and g-1?
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    I did the movement essay, linked movement of oxygen to cells with aerobic respiration to produce ATP for loads of other processes (muscle contraction, glucose co-transport etc). Anyone else take that approach/ a similar one?

    I thought the paper was OK overall
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    Oh my gosh I think I messed the hell up - for the control one the first one I talked about :
    -siRNA binding to mRNA and controlling it by not allowing it to do translation
    -Control of the movement of phagocytosis on pathogens
    -Movement of H+ in respiration
    -movement of Calcium in presyanpic neurone
    —and something else that I’ll add if I can remember
    Someone please help
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    (Original post by ppjk)
    I got 33 for number of mitochondria in calculation
    I got 5112
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    (Original post by ppjk)
    Why use micrometers and g-1?
    I put micrometres to make it easier to read off the graph, and g-1 for comparison between different masses of soil
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    (Original post by vinufailchem3)
    What were the two essay titles?
    the importance of control of movement in cells and organisms q2 : the importance of interactions between cells and between organisms
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    What did you guys get for the question about the haemoglobin and why the right and bottom are not counted???
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    (Original post by Quantum18)
    I got 5112
    me too!
    Online

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    control of movement:

    calcium ions controlling muscle movement
    spindle fibres controlling chromosome movement
    carrier protein specificity controlling movement across membranes
    insulin controlling movement of glucose into cells
    muscle tissue in arteries controlling movement of blood in vessels
    control of movement of sodium and potassium ions in nerves by voltage gated channels

    do these sound okay?
 
 
 
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