What subjects are you taking?
Keeping your files tidy and organised is important - most teachers spend their time actually teaching rather than checking to see if you have everything in order (or at least they ought to!). How to do this depends on subjects...for maths, I simply had an exercise book for each teacher (e.g. one for core maths and one for statistics) and that was sufficient. They were never looked at because we had to do homework on paper rather than handing in books (and then ending up with no book to write the next homework in!).
For biology and psychology, I started off keeping my notes and assignments in the order that I'd completed them, and eventually moved to organising them by which section of the specification they belonged to - that was a lot better for revision.
Submitting work also depends on subjects/teachers. If the teacher doesn't specify, then just ask, they won't mind!