None really. While there are some skills which are always needed in the workplace (such as team-working and communication skills), it's entirely down to your own willingness and ability to adapt and respond to the needs and demands of your employer(s)/client(s) throughout your career which will determine your long-term job prospects and your value in the job market.
A degree is an academic endeavour rather than something which is particularly tailored to the workplace. In general, a university education is of little use when it comes to training for new hands-on vocational skills. The day-to-day skills you'll use in any job will change and evolve; all you can do is keep up. It's really up to you throughout your career to either put yourself in a position where you're learning new skills on the job (and making sure you never stagnate by staying in the same job for too long), or actively seeking out training outside of the workplace.
When it comes to choosing a degree, the best thing to do is choose something you enjoy. The first few years of your career are really the only point in your life when your degree really has any meaningful effect on your employability prospects; once you're established into a particular career it's largely irrelevant to you.
Aside from the fact the passage of time will cause your university memories to fade; you'll be judged far more on the things you'll have achieved and learned in the years since graduating; particularly on the value that your skills and experience can bring to a company or client who's looking to hire you.