egoisticynical
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What’s collagen’s structure? Is it secondary or quaternary? Im confused? Please give a reason as well. Thanks!
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Fay_Fife
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It has quaternary structure (as well as secondary and tertiary structure), because it exists as a triple helix with three separate collagen polypeptides twisted together forming a rope-like structure called a fibril. Each polypeptide has a repetitive structure, and the three polypeptides in a single fibril may be the same, or translated from separate but similar genes.
Last edited by Fay_Fife; 2 years ago
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macpatgh-Sheldon
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Very good answer by Faye from Scotland (?? ) above:

A little extra information if you are heading for A* in A level biology:-

Collagen is rich in the amino acids glycine and proline with the proline residues being hydroxylated to make hydroxyproline.

Also, there are at least 20 different types of collagen;
a) in the sclera of the eye [the outer coat apart from the cornea in front] has collagen fibres of varying diameter, which makes the sclera opaque.
b) the cornea contains Type I and Type IV collagen, and the fibres are arranged in a very symmetrical, ordered lattice of uniform diameter, making the cornea transparent so that light can penetrate and permit vision.
c) collagen is found in skin, tendons, cartilage.
d) Vitamin C (ascorbic acid) is necessary for the synthesis of collagen - hence the slow healing in scurvy (disease due to deficiency of Vitamin C).

Best of luck!

M (specialist biology tutor).
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